Premium Modified GRF (1-29) 5mg (aka CJC-1295 w/o DAC)

Premium Mod-GRF 5 mg (Modified GRF (1-29) / CJC-1295 without DAC)

Overview

Modified GRF (1-29), also known as CJC-1295 without DAC, is a synthetic peptide in the growth hormone-releasing hormone (GHRH) family. It is widely studied in biochemical and physiological research for its ability to stimulate the natural release of growth hormone (GH) from the pituitary gland.

This Premium 5 mg version offers the same high-purity formulation as the standard 2 mg product but in a larger quantity for extended research use.

Mod-GRF (1-29) lacks the Drug Affinity Complex (DAC) component found in other CJC-1295 analogues, resulting in a shorter half-life while retaining full biological potency. This makes it especially suitable for investigating pulsatile GH secretion and natural endocrine signalling patterns.

Scientific Background

Growth hormone plays a central role in cell growth, metabolism, repair, and regeneration. Mod-GRF (1-29) represents the biologically active fragment of endogenous GHRH — the first 29 amino acids responsible for receptor binding and activity.

By mimicking this natural sequence, Mod-GRF (1-29) triggers GH release from the pituitary in a rhythmic, physiological manner, closely resembling the body’s own pattern.

This makes it a key model for exploring hormonal regulation, growth factor pathways, and metabolic adaptation in research settings.